Three multi-nephron vasa recta models of the renal concentrating mechanism are presented. These models are physiologically more realistic than our shunt vasa recta models. It is also shown that by considering the effects of fractional transmural fluxes between tubes and role of the interstitium in t
Renal concentrating mechanism: Central core and vasa recta models
โ Scribed by R.P. Tewarson; I.H. Moon
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 338 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0893-9659
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โฆ Synopsis
Mathematical models are essential in testing alternative hypotheses to explain the concentrating mechanism of the mammalian kidney. The basis features of a central core and two other vasa recta models, as well as efficient modeling techniques are described. It is shown that, by suitable choice of a few parameters, the two vasa recta models lead to the same osmolality and concentration ratios as the central core model.
๐ SIMILAR VOLUMES
Using an inner medullary shunt model of the kidney concentrating mechanism, we investigate the relationship between z-salt and urea concentrations in the Cent& Core, and h-water, salt and urea permeabilities in the He&e's loop and the Collecting Duct. Computational results are given comparing (a) th