Models of kidney concentrating mechanism: relationship between core concentrations and tube permeabilities

✍ Scribed by R.P. Tewarson

• Publisher: Elsevier Science
• Year: 1993
• Tongue: English
• Weight: 223 KB
• Volume: 6
• Category: Article
• ISSN: 0893-9659
• DOI: 10.1016/0893-9659(93)90081-w

✦ Synopsis

Using an inner medullary shunt model of the kidney concentrating mechanism, we investigate the relationship between z-salt and urea concentrations in the Cent& Core, and h-water, salt and urea permeabilities in the He&e's loop and the Collecting Duct. Computational results are given comparing (a) the direct problem: given h compute Z, to (b) the inverse problem: given z compute h. Mammals maintain the volume and composition of their body fluids within very narrow limits. A 'Research supported by NIH Grants DK1759314.