𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Renal cell carcinomas in trichloroethene(TRI) exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumour suppressor gene

✍ Scribed by Thomas Brüning; Gregor Weirich; M. A. Hornauer; Heinz Höfler; Hiltrud Brauch


Book ID
105871469
Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
131 KB
Volume
71
Category
Article
ISSN
0340-5761

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Somatic von Hippel–Lindau disease gene m
✍ Minoru Yoshida; Masahiro Yao; Isao Ishikawa; Takeshi Kishida; Yoji Nagashima; Ke 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 457 KB 👁 1 views

## Abstract It has been documented that renal cell carcinomas (RCCs) occur frequently in patients treated with long‐term dialysis, especially in cases of end‐stage renal disease (ESRD)/acquired cystic disease of the kidney (ACDK). To address the molecular pathogenesis of ESRD/ACDK‐associated RCCs,

Inactivation of the von Hippel–Lindau (V
✍ Steven C. Clifford; Amanda H. Prowse; Nabeel A. Affara; Charles H. C. M. Buys; E 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 149 KB 👁 2 views

Inactivation of tumour suppressor gene(s) (TSGs) on 3p appears to be a critical event in the pathogenesis of clear cell renal cell carcinoma (CC-RCC). Analysis of loss of heterozygosity (LOH) in sporadic RCC samples has implicated roles for TSGs in three specific regions of 3p in RCC development: (1