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Removal and inactivation of viruses during the manufacture of a high-purity antihemophilic factor IX from human plasma

✍ Scribed by In Seop Kim; Jung Eun Bae; Hark Mo Sung; Yong Kang; Yong Woon Choi

Book ID
107638078
Publisher
The Korean Society for Biotechnology and Bioengineering
Year
2009
Tongue
English
Weight
459 KB
Volume
14
Category
Article
ISSN
1226-8372

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## Abstract Recent reports have suggested an increased risk of type A viral hepatitis in hemophilic patients treated with high purity factor VIII concentrates prepared using ion exchange chromatography coupled with solvent/detergent treatment for in‐activation of viruses. To determine the capacity