Removal and inactivation of hepatitis A virus during manufacture of urokinase from human urine
β Scribed by In Seop Kim; Yong Woon Choi; Sung Rae Lee; Yong Kang; Kyung Myung Lee; Dae Han Park; Han Sang Woo; Soungmin Lee
- Publisher
- The Korean Society for Biotechnology and Bioengineering
- Year
- 2002
- Tongue
- English
- Weight
- 186 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1226-8372
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The efficacy of two heating cycles (90 sec at 103 O C and 10 hr at 65 "C) used during manufacture of a plasma-derived hepatitis-B vaccine was validated for the inactivation of 12 virus families. A period of 15 min warming up to 65 O C had already completely inactivated representatives of nine virus
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