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Remote Protection Prevents Unwanted Cyclizations with 2-Aminopyridines.

✍ Scribed by Graham R. Lawton; Haitao Ji; Richard B. Silverman


Book ID
101993281
Publisher
John Wiley and Sons
Year
2006
Weight
15 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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πŸ“œ SIMILAR VOLUMES


Stereocontrolled cyclization of enynols
✍ Hirokazu Urabe; Fumie Sato πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 235 KB

Stereochemistry of (r/2-propene)Ti(O-i-Pr)2-mediated cyclization of enynols and allenynols is efficiently controlled by their remote hydroxy group, showing good diastereoselectivities as high as 82:18-98.5:1.5, which are uniformly superior to those observed for the corresponding t-BuMe2Si ethers.