New quinolones 3, 6 and 9 mmelated to either a 5-raembered or a 6-membered lactone were designed as hybrids of antibacterial 4-quinolones and antitumor epipodophyllotoxin derivatives. They were synthezised using ethyl 2-ethenyl-4-hydroxy-l,2-dihydroquinoline-3-carboxylate 2 as a key intermediate.
✦ LIBER ✦
Remote functionalization (1): Synthesis of γ- and δ-lactones from aromatic carboxylic acids
✍ Scribed by Hideo Togo; Takahito Muraki; Masataka Yokoyama
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 195 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
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