Rel/NF-κB transcription factors and the control of apoptosis
✍ Scribed by Gail E. Sonenshein
- Book ID
- 112264894
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 117 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1044-579X
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## Abstract ## BACKGROUND Primary hepatocellular carcinoma (HCC) is one of the 10 most common human carcinomas in the world. The mechanism by which HCC cells resist apoptosis induced by various treatment modalities is poorly understood. ## METHODS The authors sought to determine whether Rel/NF‐κ
The activation of B and T cells by a wide range of stimuli can rapidly induce specific gene expression via a mechanism that promotes the nuclear translocation of different Rel/nuclear factor-kappa B (NF-kappa B) transcription factors which are normally resident in the cytoplasm. Recent findings high