Escherichia coli was depleted of ribosomes by a thermal shock at 47 degrees C which quantitatively destroyed the 30S ribosomal subunits. During recovery in minimal medium at 30 degrees C RNA is synthesized while protein synthesis resumes only after about 90 min. It is shown that lac mRNA is synthesi
Relief of Polarity in E. coli by “suA”
✍ Scribed by MORSE, DANIEL E.; PRIMAKOFF, PAUL
- Book ID
- 109671730
- Publisher
- Nature Publishing Group
- Year
- 1970
- Tongue
- English
- Weight
- 454 KB
- Volume
- 226
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/226028a0
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In Escherichia coli, 3'5'-adenosine cyclic monophosphate (cAMP) and its receptor protein (CAP) are known to be involved in the control of transcription initiation of catabolic operons. In previous papers we have shown that the cAMP-CAP complex is also involved as a modulator of polarity in polycistr
Phenotypic revertants of galOP::IS1 and galOP::IS2 mutations have been isolated after mutagenesis with nitrosoguanidine, they are probably caused by mutations in gene suA. The polarity suppressor mutations described in this study and a known mutation in gene suA isolated by D. Morse (Morse and Guert