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Release kinetics of 5-aminosalicylic acid from halloysite

✍ Scribed by Aguzzi, C.; Viseras, C.; Cerezo, P.; Salcedo, I.; Sánchez-Espejo, R.; Valenzuela, C.


Book ID
122438135
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
436 KB
Volume
105
Category
Article
ISSN
0927-7765

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Pharmacokinetics of 5-aminosalicylic aci
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One gram single dose of Pentasa controlledrelease capsules was administered to 24 healthy volunteers under fasting condition. Mean plasma 5-aminosalicylic acid (5-ASA) and acetyl 5-ASA concentrations peaked at 0.53 gg' m1-1 and 1.33 gg. m1-1 from 3 to 4 hours following dosing, respectively. The half