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Relaxant effect of quinoline derivatives on histamine-induced contraction of the isolated guinea pig trachea

✍ Scribed by Chi-Hoon Lee; Hoi-Seon Lee


Book ID
119936619
Publisher
The Korean Society for Applied Biological Chemistry
Year
2011
Tongue
English
Weight
198 KB
Volume
54
Category
Article
ISSN
1738-2203

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Antigen (ovalbumin)-induced contraction of guinea-pig isolated trachea, which largely resulted from the endogenous release of peptidoleukotrienes, was strongly inhibited by the non-selective phosphodiesterase (PDE) inhibitor theophylline and, more potently, by the selective PDE type IV inhibitors ro