Amplification and overexpression of the
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Jiro Ishikawa; Sakan Maeda; Kei-Ichi Umezu; Taketoshi Sugiyama; Sadao Kamidono
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Article
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1990
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John Wiley and Sons
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French
โ 512 KB
We examined 22 cases of renal-cell carcinoma (RCC) for structural alterations of the epidermal growth factor receptor (ECFR) gene and found gene amplification in one case of high-stag+high-grade RCC. Dot blot analysis of the total RNA from tumorous and normal kidney tissues revealed overexpression o