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Relationship of inherent resistance to doxorubicin, proliferative activity and expression of P-glycoprotein 170, and glutathione S-transf erase-π in human lung tumors

✍ Scribed by Manfred Volm; JÜRgen Mattern; Barbara Samsel


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
628 KB
Volume
70
Category
Article
ISSN
0008-543X

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✍ Efferth, T. ;L�hrke, H. ;Volm, M. 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 563 KB

The natural resistance to doxorubicin of 15 human renal carcinoma cell lines was analyzed and compared to proliferative activity and expression of P-glycoprotein. We found a significant negative correlation between proliferative activity and natural resistance to doxorubicin, as well as between prol