Relationship of genotypes of hepatitis B virus to mutations, disease progression and response to antiviral therapy
โ Scribed by A. Kramvis; M. C. Kew
- Book ID
- 108885787
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 96 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1352-0504
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## Abstract Using phylogenetic analysis and pairwise comparison of 670 complete hepatitis B virus (HBV) genomes, we demonstrated that nucleotide divergence greater than 7.5% can be used to separate strains into genotypes AโH. Strains can be separated into subgenotypes when two criteria are met: nuc