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Relationship of bone morphogenetic protein expression during osteoblast differentiation to wild type p53

โœ Scribed by Nalini Chandar; John Swindle; Ann Szajkovics; Kevin Kolman


Book ID
113834668
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
419 KB
Volume
23
Category
Article
ISSN
0736-0266

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Relationship of bone morphogenetic prote
โœ Nalini Chandar; John Swindle; Ann Szajkovics; Kevin Kolman ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 930 KB

We have previously shown p53 to have a specific role in osteoblast differentiation by its ability to regulate expression of certain bone specific proteins. In this study, we show mineralized matrix formation in vivo to be directly related to the presence of wild type p53 in osteoblastic osteosarcoma