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Relationship between the duration and number of cell cycles after mutagenic exposure and the incidence of sister chromatid exchanges

✍ Scribed by S. M. Kuzin; S. V. Stukalov


Publisher
Springer US
Year
1998
Tongue
English
Weight
217 KB
Volume
125
Category
Article
ISSN
0007-4888

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Although sister-chromatid exchange (SCE) analysis is recognized as an indicator of exposure to DNA-damaging agents, the results of these analyses have been confounded by the use of bromodeoxyuridine (BrdUrd) to differentially label the sister chromatids. Not only does BrdUrd itself induce SCE, it al