Nine analogues of lurlenic acid {(4E,8E,12E)-14-[2Ј-hydroxy-nate (7), butyl lurlenate (8), the bisdemethyl analogue 9, and the 2Ј-deoxy-2Ј-methyl analogue 10. Structural requirements 3Ј,4Ј-dimethyl-5Ј-(1Љ-β-D-xylopyranosyloxy)phenyl]-4,8,12trimethyltetradeca-4,8,12-trienoic acid (1)}, a component of
✦ LIBER ✦
Relationship between structure and intestinal absorption of bile acids with a steroid or side-chain modification
✍ Scribed by Rita Aldini; Aldo Roda; Marco Montagnani; Carolina Cerre; Roberto Pellicciari; Enrico Roda
- Book ID
- 117213771
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 837 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0039-128X
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In order to clarify structure-activity relationships, nine analogues of the title pheromone (I), which are modified in the side-chain or in the aromatic nucleus, are prepared. The structural requirements for the expression of the pheromonal activity is briefly discussed. The work confirms the import