Relationship between regulatory and type 1 T cells in dogs with oral malignant melanoma
โ Scribed by Yutaka Horiuchi; Makiko Tominaga; Mika Ichikawa; Masao Yamashita; Kumiko Okano; Yuri Jikumaru; Yoko Nariai; Yuko Nakajima; Masato Kuwabara; Masayoshi Yukawa
- Book ID
- 108578389
- Publisher
- Center for Academic Publications, Japan
- Year
- 2010
- Tongue
- English
- Weight
- 489 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0385-5600
No coin nor oath required. For personal study only.
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## Abstract ## Background Homeostasis of circulating T cells is regulated in complex ways that have not yet been well defined. The balance between type 1 and type 2 Tโcell subsets in cancer patients is thought to modulate antitumor immunity. Meanwhile, CD4+CD25+ regulatory T cells (Treg), which ar
Mutations of forkhead box p3 (__FOXP3__), the master gene for naturally occurring regulatory T cells (nTregs), are responsible for the impaired function of nTregs, resulting in an autoimmune disease known as the immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome. The rel