p21WAF1/CIP1expression in stage I cutaneous malignant melanoma: its relationship with p53, cell proliferation and survival
β Scribed by Karjalainen, J M; Reinikainen, M; Kosma, V-M
- Book ID
- 110001007
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 319 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0007-0920
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Defects in the mechanisms controlling the cell cycle are crucial in cell transformation and/or tumour progression. p21 WAF1/CIP1 is an inhibitor of cyclin-dependent kinases, induced by p53-dependent and p53-independent pathways, which can block progression through the cell cycle. p21 WAF1/CIP1 expre
## Abstract Ribosomal biogenesis is correlated with cell cycle, cell proliferation, cell growth and tumorigenesis. Some oncogenes and tumor suppressors are involved in regulating the formation of mature ribosome and affecting the ribosomal biogenesis. In previous studies, the mitochondrial ribosoma
The immunoreactivity of p21 was evaluated in normal mucosa and in adenomas and adenocarcinomas of the human large bowel. In normal mucosa, p21 immunoreactivity was seen in the superficial third of the crypts (maturation compartment) and in surface (terminally differentiated) epithelium, and was mutu