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Relationship between morphologic features and hardness of the subchondral bone of the medial tibial condyle in the normal state and in osteoarthritis and rheumatoid arthritis

โœ Scribed by Paul Lereim; Ian F. Goldie


Publisher
Springer
Year
1975
Tongue
English
Weight
809 KB
Volume
81
Category
Article
ISSN
1434-3916

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โœฆ Synopsis


In osteoarthritis and rheumatoid arthritis the hardness of the subchondral bone of the medial tibial plateau is lower than in normals. In order to further analyse this study of the morphologic characteristics in bone from the mentioned region was carried out in 22 normals, 14 osteoarthritis and 12 rheumatoid arthritis. Specimens from these groups were subjected to a radiologic assay, a light microscopic investigation and an evaluation of the occurrence of intraosseous lipids. The normals showed a remarkable integrity of the subchondral trabecular network with advancing age only with slight osteoporosis and occasional sclerosis. In osteoarthritis there were osteoporosis, osteolysis, sclerosis and osteophytes all in good correlation to the grade of osteoarthritis present. In rheumatoid arthritis there were areas of rarefaction, fractures of the trabeculae, sclerosis and invasion of granulation tissue. The radiologic appearance corresponded well with the morphologic observation. No abnormal presence of lipids was encountered. This investigation supports the concept that the hardness of the subchondral bone of the medial tibial plateau much depends on the morphologic structure of the bone.


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The presence of alkaline phosphatase in
โœ Paul Lereim; Anders Linde; Jan F. Goldie ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› Springer ๐ŸŒ English โš– 355 KB

A study has been carried out on the alkaline phosphatase activity in trabecular bone in the normal state, rheumatoid arthritis and osteoarthritis. Samples were taken from the subchondral bone of the medial tibial condyle in all cases. The reason for this study was to investigate whether changes in r