𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Relationship between insulin dose, body weight and glycaemic control in insulin-dependent diabetes

✍ Scribed by Gill, G ;Hardy, K ;Lorains, J

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
192 KB
Volume
11
Category
Article
ISSN
1357-8170

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The relationships between daily insulin dose, body weight, age, sex and glycosylated haemoglobin (HbA~1~) were explored in a group of 198 insulin‐dependent (IDDM) diabetics of at least five years' duration. Insulin dose was positively correlated with body weight (p<0.001), and negatiely related to age (p<0.005). Doses in units/kg were also higher in males when compared with females (0.76 Β± 0.25 v 0.61 Β± 0.20 Β± u/kg, p<0.001). There was no correlation between insulin dose and HbA~1~.

Higher insulin requirements in males, a positive relationship with body weight, together with declining requirements with age, suggests a possible dependence of insulin dose on lean body mass. The lack of relationship between insulin dose and HbA~1~ is perhaps disappointing, but may reflect the many factors affecting insulin absorption and action, as well as perhaps the destabilising effects of β€˜over‐insulinisation’.

πŸ“œ SIMILAR VOLUMES

Poor glycaemic control and retinopathy i
Poor glycaemic control and retinopathy in non-insulin-dependent diabetes mellitus
✍ Bastyr III, E.J.; Janes, J.; Barnett, A.H. πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 30 KB πŸ‘ 2 views

## References endothelial cell leukocyte adhesion plored in twin studies. Hawkes 1 accepts molecules in atherosclerosis. Thromthe high concordance in MZ twins for 1. Hawkes CH. Twin studies in diabetes bosis and Haemostasis 1994; 72: Type 1 diabetes in a study where insulin mellitus. Diabetic Med

Long-term glycaemic control achieved in
Long-term glycaemic control achieved in young insulin-dependent diabetics
✍ McLaren, E H ;Lakhdar, A A ;McLellan, I πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 357 KB

## Abstract The long‐term glycaemic control, assessed by the mean of three successive levels of glycosylated haemoglobin (HbA~1c~) achieved in a special clinic for insulindependent diabetics aged 12–40, was audited in 1984 and 1987. Clinic policy involved a twice‐daily insulin regimen with infreque

Alcohol Ingestion and Glycaemic Control
Alcohol Ingestion and Glycaemic Control in Patients with Insulin-dependent Diabetes Mellitus
✍ Meeking, D.R.; Cavan, D.A. πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 123 KB πŸ‘ 2 views

It is widely accepted that alcohol consumption by patients with insulin-dependent (Type 1) diabetes mellitus is associated with an increased risk of hypoglycaemia. This association has been the subject of few studies, however, and there is not much evidence to support advice currently given to patie