The aim of the present study was to evaluate the role of residual insulin production in long-term Type 1 (insulin-dependent) diabetes mellitus. Ninety-seven patients with a disease duration of 9-16 years and onset before the age of 30 years were studied. C-peptide excretion in 24-h urine samples was
Long-term glycaemic control achieved in young insulin-dependent diabetics
โ Scribed by McLaren, E H ;Lakhdar, A A ;McLellan, I
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 357 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1357-8170
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โฆ Synopsis
Abstract
The longโterm glycaemic control, assessed by the mean of three successive levels of glycosylated haemoglobin (HbA~1c~) achieved in a special clinic for insulindependent diabetics aged 12โ40, was audited in 1984 and 1987. Clinic policy involved a twiceโdaily insulin regimen with infrequent blood glucose monitoring and little emphasis on dietary compliance or formal education. Overall levels of diabetic control were identical in 1984 and 1987; 34% of patients had HbA levels within three standard deviations of the mean and 60% within five standard deviations. There was no correlation between control and age or duration of diabetes. Diabetic control deteriorated in 24% of patients and improved in 20% between 1984 and 1987. There was no significant difference in the overall levels of control compared with other centres. It is concluded that frequent blood glucose monitoring, strict dietary compliance and formal education are not important factors in glycaemic control in insulinโdependent diabetes.
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