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Relationship between hepatitis B virus (HBV) genotype and the precore mutant in anti-HBe(+) patients before and after liver transplantation (LT)

โœ Scribed by Ziv Ben-Ari; Yaffa Ashur; Nili Daudi; Hemda Wiess; Jaqueline Sulkes


Book ID
118565262
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
108 KB
Volume
36
Category
Article
ISSN
0168-8278

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Hepatitis B virus DNA clones were propagated from sera of six patients with chronic hepatitis B who seroconverted from HBeAg to antibody to HBeAg either spontaneously or after administration of Q- interferon. Defects in the precore region blocking synthesis and secretion of HBeAg were detected in al