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Relation of biological activity of mutant forms of recombinant human tumor necrosis factor alpha and accumulation of sphingosine in murine liver

✍ Scribed by A. V. Alessenko; V. G. Korobko; A. V. Khrenov; U. A. Rozhnova; A. S. Soloviev; L. N. Shingarova

Book ID: 111742384
Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 647 KB
Volume: 42
Category: Article
ISSN: 1521-6543
DOI: 10.1080/15216549700202521

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## Abstract The antitumor activity of highly purified tumor necrosis factor (TNF) was tested against eight kinds of murine tumor and five kinds of human tumor heterotransplanted into nude mice. Mice were treated by intravenous or intratumoral injection of TNF, commencing when the tumors were well e