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Relating Macromolecular Function and Association: The Structural Basis of Protein–DNA and RNA Recognition

✍ Scribed by Joël Janin; Ranjit P. Bahadur

Book ID
107620643
Publisher
Springer
Year
2008
Tongue
English
Weight
532 KB
Volume
1
Category
Article
ISSN
1865-5025

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✍ Linda Jen-Jacobson 📂 Article 📅 1997 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 665 KB

This paper considers how enzymes that catalyze reactions at specific DNA sites have been engineered to overcome the problem of competitive inhibition by excess nonspecific binding sites on DNA. The formation of a specific protein-DNA recognition complex is discussed from both structural and thermody