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Relapsing subacute demyelinating encephalomyelitis in rats during the course of coronavirus JHM infection

✍ Scribed by Helmut Wege; Rihito Watanabe; Volker ter Meulen


Book ID
119106603
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
681 KB
Volume
6
Category
Article
ISSN
0165-5728

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Intracerebral infection of rats with JHM coronavirus induces a chronic inflammatory demyelinating disease, which in many respects mimicks the pathology of multiple sclerosis. We investigated the patterns of demyelination and oligodendrocyte pathology in this model. In early stages of the disease inf