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Coronavirus JHM induced demyelinating encephalomyelitis in rats: Analysis of the intrathecal immune response

✍ Scribed by R. Dörries; S. Schwender; H. Wege; H. Harms; V. ter Meulen


Book ID
119106933
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
119 KB
Volume
16
Category
Article
ISSN
0165-5728

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Intracerebral infection of rats with JHM coronavirus induces a chronic inflammatory demyelinating disease, which in many respects mimicks the pathology of multiple sclerosis. We investigated the patterns of demyelination and oligodendrocyte pathology in this model. In early stages of the disease inf