Reirradiation plus EGFR inhibition in locally recurrent and unresectable head and neck cancer
✍ Scribed by D. Milanović M.D., B. Jeremić M.D., Ph.D.…
- Book ID
- 120918128
- Publisher
- Springer
- Year
- 2013
- Tongue
- German
- Weight
- 553 KB
- Volume
- 189
- Category
- Article
- ISSN
- 0179-7158
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## Abstract ## Background. The management of recurrent unresectable head and neck cancer remains a challenging problem. Based on the circadian rhythm concept, we sought to determine the maximum tolerated dose (MTD) of infusional 5‐flourouracil (5‐FU), hydroxyurea (HU), and reirradiation (RT). ##
## Abstract ## Background In this retrospective investigation we analyzed outcome and toxicity after intensity‐modulated reirradiation of recurrent head and neck cancer. ## Methods Thirty‐eight patients with local recurrent head and neck cancer were evaluated. The median dose of initial radiothe