Regulatory T cells in lung transplantation—an emerging concept
✍ Scribed by David C. Neujahr; Christian P. Larsen
- Book ID
- 105995130
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 329 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1863-2297
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There has been considerable recent progress in the characterization of the regulatory T cells that mediate tolerance in a number of transplantation models. The conditions that facilitate the generation of regulatory T cells point to the thymus, the nature of immune suppression and the dose of immuno
## Abstract For Abstract see ChemInform Abstract in Full Text.
Immune regulatory CD4 ϩ CD25 ϩ T cells play a crucial role in inducing and maintaining allograft tolerance in experimental models of transplantation (Tx). In humans, the effect of Tx and immunosuppression on the function and homeostasis of CD4 ϩ CD25 ϩ regulatory T cells (Tregs) is not well characte