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Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

✍ Scribed by Wan, Yisong Y.; Flavell, Richard A.


Book ID
109896429
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
706 KB
Volume
445
Category
Article
ISSN
0028-0836

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## Background: Cd4+cd25+ regulatory t cells (tr) can prevent or treat experimental murine colitis but little is known about their potential role in human inflammatory bowel disease (ibd). foxp3 is a transcription factor that plays a critical role in the development and function of cd4+cd25+ tr. the