𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The critical contribution of TGF-β to the induction of Foxp3 expression and regulatory T cell function

✍ Scribed by Ethan M. Shevach; Dat Q. Tran; Todd S. Davidson; John Andersson

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
106 KB
Volume
38
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression and functional characterizati
Expression and functional characterization of FOXP3+CD4+ regulatory T cells in ulcerative colitis
✍ Qi T. Yu; Masayuki Saruta; Armine Avanesyan; Phillip R. Fleshner; Alison H. Banh 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 470 KB 👁 1 views

## Background: Cd4+cd25+ regulatory t cells (tr) can prevent or treat experimental murine colitis but little is known about their potential role in human inflammatory bowel disease (ibd). foxp3 is a transcription factor that plays a critical role in the development and function of cd4+cd25+ tr. the

N-Ras or K-Ras inhibition increases the
N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells
✍ Adi Mor; Gad Keren; Yoel Kloog; Jacob George 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB 👁 1 views

## Abstract Naturally occurring regulatory T cells (Treg) driven by their transcriptional controller Foxp3 are compromised in immune‐mediated disorders and confer protection when adoptively transferred. We examined the Ras‐inhibitory effect on functional determinants of Treg __in vivo__ and __in vi

c-Rel is crucial for the induction of Fo
c-Rel is crucial for the induction of Foxp3+ regulatory CD4+ T cells but not TH17 cells
✍ Alexander Visekruna; Magdalena Huber; Anne Hellhund; Evita Bothur; Katharina Rei 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB 👁 1 views

## Abstract The NF‐κB/Rel family member c‐Rel was described to be required for the development of T~H~1 responses. However, the role of c‐Rel in the differentiation of T~H~17 and regulatory CD4^+^Foxp3^+^ T cells (Treg) remains obscure. Here, we show that in the absence of c‐Rel, __in vitro__ diffe