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Regulatory T-cell development: is Foxp3 the decider?

โœ Scribed by Curiel, Tyler J


Book ID
109927425
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
463 KB
Volume
13
Category
Article
ISSN
1078-8956

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## Abstract FOXP3 is a specific marker for naturally occurring regulatory T cells (nTreg). FOXP3 expression is correlated with development and function of nTreg. Recent evidence suggests that, upon activation, human effector T (Teff) cells and type 1 regulatory T (Tr1) cells can express FOXP3, albe