Regulatory T Cell Abnormalities Associated with Aberrant CD4+ T Cell Responses in Patients with Immune Reconstitution Disease (IRD)
β Scribed by Nabila Seddiki
- Book ID
- 113539716
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 55 KB
- Volume
- 123
- Category
- Article
- ISSN
- 1090-2341
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The role of Treg in patients with lateβstage HIV disease, who commence combination antiretroviral therapy (cART) and develop pathogenβspecific immunopathology manifesting as immune restoration disease (IRD) remains unclear. We hypothesised that Treg could be defective in either numbers
## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the downβregulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos