Regulatory elements of human renin gene expression
β Scribed by David W. Burt; Pamela Kelley; Julie Flynn; Allen Naftilan; Victor J. Dzau
- Book ID
- 119442890
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 70 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0022-2828
No coin nor oath required. For personal study only.
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## Abstract The regulation of __renin__ gene expression, the rateβlimiting enzyme of the system, is thought to be fundamental to the total system. Previously, we mapped six putative __cis__βelements in the promoter region of the human __renin__ gene with nuclear proteins from human chorionic cells
## Abstract The regulation of renin gene expression is thought to be fundamental to regulation of the total reninβangiotensin system. The human renin gene contains a direct repeat (DR) motif AGGGGTCACβAGGGCCA in the proximal region (β259/β245 bp), which contains similar sequence for nuclear recepto