Regulation of β-actin gene transcription by insulin and phorbol esters
✍ Scribed by Joseph L. Messina; Ruth S. Weinstock
- Book ID
- 115892707
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 394 KB
- Volume
- 200
- Category
- Article
- ISSN
- 0014-4827
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Insulin exerts rapid effects on cellular metabolism and can cause morphological changes by inducing rearrangements of cytoskeletal components. The regulation of specific cytoskeletal genes by insulin, however, has not been studied extensively. In the present work insulin was found to rapidly, but tr
## Regulation of immunoglobulin gene expression in trans by phorbol esters* Lipopolysaccharide-stimulated B cell cultures treated with phorbol-12,13-dibutyrate have been shown to down-regulate their steady state levels of ps RNA while the pm RNA remained constant. In contrast, the steady state lev