𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Regulation of type I collagen synthesis : Total proα1(I) and proα2(I) mRNAs are maintained in a 2: 1 ratio under varying rates of collagen synthesis

✍ Scribed by Jens VUUST; Mark E. SOBEL; George R. MARTIN

Book ID
115123197
Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
907 KB
Volume
151
Category
Article
ISSN
1432-1327

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Transfer of proα2(I) cDNA into cells of
Transfer of proα2(I) cDNA into cells of a murine model of human Osteogenesis Imperfecta restores synthesis of type I collagen comprised of α1(I) and α2(I) heterotrimers in vitro and in vivo
✍ Christopher Niyibizi; Patrick Smith; Zhibao Mi; Charlotte L. Phillips; Paul Robb 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 197 KB

## Abstract The __oim__ mouse is a model of human Osteogenesis Imperfecta (OI) that has deficient synthesis of proα2(I) chains. Cells isolated from __oim__ mice synthesize α1(I) collagen homotrimers that accumulate in tissues. To explore the feasibility of gene therapy for OI, a murine proα2(I) cDN