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Regulation of tumor necrosis factor (TNF) expression: Interferon-γ enhances the accumulation of mRNA for TNF induced by lipopolysaccharide in murine peritoneal macrophages

✍ Scribed by T.J. Koerner; Dolph O. Adams; Thomas A. Hamilton


Book ID
113133997
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
802 KB
Volume
109
Category
Article
ISSN
0008-8749

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✍ George E. Gifford; Marie-Luise Lohmann-Matthes 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 French ⚖ 341 KB 👁 1 views

This work demonstrates the need for the continued presence of lipopolysaccharide (LPS) for tumor necrosis factor (TNF) production by thioglycollate-induced peritoneal macrophages. Removal of LPS at any time resulted in the abrupt cessation of further TNF production. The readdition of LPS resulted in