✦ LIBER ✦

Requirement for the continual presence of lipopolysaccharide for production of tumor necrosis factor by thioglycollate-induced peritoneal murine macrophages

✍ Scribed by George E. Gifford; Marie-Luise Lohmann-Matthes

Publisher: John Wiley and Sons
Year: 1986
Tongue: French
Weight: 341 KB
Volume: 38
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910380121

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✦ Synopsis

This work demonstrates the need for the continued presence of lipopolysaccharide (LPS) for tumor necrosis factor (TNF) production by thioglycollate-induced peritoneal macrophages. Removal of LPS at any time resulted in the abrupt cessation of further TNF production. The readdition of LPS resulted in further production of TNF but the yield was limited to the amount that would have been produced had the LPS not been removed.

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