Regulation of the initiation of chromosomal replication in bacteria
✍ Scribed by Jolanta Zakrzewska-Czerwińska; Dagmara Jakimowicz; Anna Zawilak-Pawlik; Walter Messer
- Book ID
- 109334909
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 137 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1574-6976
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Our understanding of the process by which eukaryotes regulate initiation of DNA replication has made remarkable advances in the past few years, thanks in large part to the explosion of genetic and biochemical information on the budding yeast, Saccharomyces cerevisiae. At least three major concepts h
## Abstract **Background:** During the cell cycle, the initiation of chromosomal replication is strictly controlled. In __Escherichia coli__, the initiator DnaA and the replication origin __oriC__ are major targets for this regulation. Here, we assessed the role of transcription of the __mioC__ gen