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Regulation of the E2F-associated phosphoprotein promoter by GC-box binding proteins

✍ Scribed by Ludwig Schwarzmayr; Peter Andorfer; Michael Novy; Hans Rotheneder


Book ID
116307621
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
752 KB
Volume
40
Category
Article
ISSN
1357-2725

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Pura is a ubiquitously expressed multifunctional nucleic acid-binding protein that is involved in many cellular processes including transcriptional regulation, the cell cycle, oncogenic transformation, and post-natal brain development. Previously, Pura protein was found to bind to E2F-1, inhibit E2F