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Regulation of the Cell Cycle at the G1–S Transition by Proteolysis of Cyclin E and p27Kip1

✍ Scribed by Kei-Ichi Nakayama; Shigetsugu Hatakeyama; Keiko Nakayama

Book ID
115587706
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
447 KB
Volume
282
Category
Article
ISSN
0006-291X

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## Abstract Proliferation of Schwann cells __in vitro__, unlike most mammalian cells, is not induced by serum alone but additionally requires cAMP elevation and mitogenic stimulation. How these agents cooperate to promote progression through the G1 phase of the cell cycle is unclear. We studied the