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Regulation of the activity of Sp1-related transcription factors

✍ Scribed by Peter Bouwman; Sjaak Philipsen


Book ID
117463148
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
353 KB
Volume
195
Category
Article
ISSN
0303-7207

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## Abstract The transcription factors Sp1, Sp3, and Egr‐1 bind with their zinc finger DNA‐binding domains to GC‐rich sequences in the regulatory regions of their target genes. The similarity of the DNA‐binding sites of Sp1, Sp3, and Egr‐1 has triggered the hypothesis that they compete for the same