Regulation of Survivin and CDK4 by Epstein-Barr virus encoded latent membrane protein 1 in nasopharyngeal carcinoma cell lines
✍ Scribed by AI, Mi Dan; LI, Li Li; ZHAO, Xiao Rong; WU, Yong; GONG, Jian Ping; CAO, Ya
- Book ID
- 110020675
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 623 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0007-0610
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## Abstract ## Background Nasopharyngeal carcinoma (NPC) is associated with Epstein–Barr virus (EBV) infection. We previously found that interleukin (IL)‐1α and IL‐1β significantly increased in NPC tissues. This study investigated what EBV‐encoded proteins were involved in such IL‐1 production. #
## Abstract Nasopharyngeal carcinoma is closely associated with Epstein‐Barr virus (EBV) and the EBV encoded latent membrane protein‐1 expression (LMP1) is commonly found in the tumour cells. LMP1 has been shown to be involved in modulation of cell growth in B cells but the biological properties of