Regulation of surfactant protein and defensin mRNA expression in cultured ovine type II pneumocytes by all-trans retinoic acid and VEGF
β Scribed by B. Grubor; D. K. Meyerholz; T. Lazic; M. M. DeMacedo; R. J. Derscheid; J. M. Hostetter; J. M. Gallup; J. C. DeMartini; M. R. Ackermann
- Book ID
- 108785751
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 572 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0959-9673
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## Abstract dHAND is thought to be a cardiacβrestricted transcription factor during embryonic development. Vertebrate heart development involves many transcription factors such as Nkx2.5, GATA, and tbx5. Allβ__trans__ retinoic acid (AtRA), the oxidative metabolite of vitamin A, can regulate the exp
In vitro human skin fibroblasts aging was characterized by a continuous increase of collagenase mRNA levels. On the contrary, TIMPβ1 mRNA level decreased only at late passages (> 65% of proliferative life span). Type I and III mRNA levels showed a high variability depending on cell strains studied.