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Regulation of recombinational repair by the familial breast cancer susceptibility protein BRCA2

✍ Scribed by SC West, F Esashi


Book ID
120700218
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
325 KB
Volume
8
Category
Article
ISSN
1465-5411

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Analysis of breast cancer susceptibility
✍ Pimpicha Patmasiriwat; Kris Bhothisuwan; Olga M. Sinilnikova; Sandrine Chopin; S πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 173 KB πŸ‘ 2 views

Here we report the study on BRCA1 and BRCA2 mutations in 12 Thai breast and/or ovarian cancer families and 6 early-onset breast or breast/ovarian cancer cases without a family history of cancer. Five distinct rare alterations were identified in each gene: four introducing premature stop codons, one