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Identification of the breast cancer susceptibility gene BRCA2

✍ Scribed by Wooster, Richard; Bignell, Graham; Lancaster, Jonathan; Swift, Sally; Seal, Sheila; Mangion, Jonathan; Collins, Nadine; Gregory, Simon; Gumbs, Curtis; Micklem, Gos

Book ID
109794775
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
849 KB
Volume
378
Category
Article
ISSN
0028-0836

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Analysis of breast cancer susceptibility
Analysis of breast cancer susceptibility genes BRCA1 and BRCA2 in Thai familial and isolated early-onset breast and ovarian cancer
✍ Pimpicha Patmasiriwat; Kris Bhothisuwan; Olga M. Sinilnikova; Sandrine Chopin; S πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 173 KB πŸ‘ 2 views

Here we report the study on BRCA1 and BRCA2 mutations in 12 Thai breast and/or ovarian cancer families and 6 early-onset breast or breast/ovarian cancer cases without a family history of cancer. Five distinct rare alterations were identified in each gene: four introducing premature stop codons, one