𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Regulation of PTEN expression in neuronal apoptosis

✍ Scribed by Sergiy Kyrylenko; Maaria Roschier; Pauliina Korhonen; Antero Salminen

Book ID
117387417
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
270 KB
Volume
73
Category
Article
ISSN
0169-328X

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## Abstract ## BACKGROUND. The tumor suppressor gene PTEN is a major negative regulator of the PI3K/Akt cellular survival pathway. Overexpression of PTEN by adenoviral transfection increases doxorubicin‐induced apoptosis. Whereas doxorubicin‐induced apoptosis can be potentiated by the histone deac