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Pten Regulates Neuronal Arborization and Social Interaction in Mice

✍ Scribed by Chang-Hyuk Kwon; Bryan W. Luikart; Craig M. Powell; Jing Zhou; Sharon A. Matheny; Wei Zhang; Yanjiao Li; Suzanne J. Baker; Luis F. Parada

Book ID
116782647
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
826 KB
Volume
50
Category
Article
ISSN
0896-6273

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## Abstract Carboxypeptidase E (CPE) is involved in maturation of neuropeptides and sorting of brain‐derived neurotrophic factor (BDNF) to the regulated pathway for activity‐dependent secretion from CNS neurons. CPE knockout (CPE‐KO) mice have many neurological deficits, including deficits in learn