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Regulation of Platelet Production: ‘Hypersplenism’ in the Experimental Animal

✍ Scribed by Geswalda de Gabriele; D. G. Penington

Book ID
117946484
Publisher
John Wiley and Sons
Year
1967
Tongue
English
Weight
524 KB
Volume
13
Category
Article
ISSN
0007-1048

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An age-structured model for the regulation of platelet production is developed, and compared with both normal and pathological platelet production. We consider the role of thrombopoietin (TPO) in this process, how TPO affects the transition between megakaryocytes of various ploidy classes, and their