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A Model for the Regulation of Mammalian Platelet Production

✍ Scribed by JACQUES BÉLAIR; MICHAEL C. MACKEY


Book ID
119860537
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
73 KB
Volume
504
Category
Article
ISSN
0890-6564

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Regulation of Platelet Production: The N
✍ MOISÉS SANTILLÁN; JOSEPH M MAHAFFY; JACQUES BÉLAIR; MICHAEL C MACKEY 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 340 KB

An age-structured model for the regulation of platelet production is developed, and compared with both normal and pathological platelet production. We consider the role of thrombopoietin (TPO) in this process, how TPO affects the transition between megakaryocytes of various ploidy classes, and their